By modelling the mass isotopomer distribution of methyl palmitate using Isotopomer Spectral Analysis ISA, a technique that untangles the effect of changes in the acetyl CoA pool contribution from the biosynthetic rate 24, it was established that the increases in 13 C tracer label incorporation were results of higher rates of de novo biosynthesis in the PIK3C
By modelling the mass isotopomer distribution of methyl palmitate using Isotopomer Spectral Analysis ISA, a technique that untangles the effect of changes in the acetyl CoA pool contribution from the biosynthetic rate 24, it was established that the increases in 13 C tracer label incorporation were results of higher rates of de novo biosynthesis in the PIK3C